While The Endocrine Society is assisting authors by fulfilling the obligation of submitting manuscripts to PMC, some authors may elect to submit their own accepted unedited manuscripts. Therefore, we ask that authors follow the instructions below:

The accepted unedited manuscript version cannot be modified when you submit to PMC. Therefore we ask that you prepare this manuscript understanding that its content should appear unaltered after submission and acceptance.

If the work described in your manuscript has been supported in whole or in part by the U.S. National Institutes of Health, you will be required to insert the following phrase on the title page of all manuscript version articles, typed immediately after the authors’ affiliations and indicated as a footnote to the title:

“This is an un-copyedited author manuscript copyrighted by The Endocrine Society. This may not be duplicated or reproduced, other that for personal use or within the rule of “Fair Use of Copyrighted Materials” (section 107, Title 17, U.S. Code) without permission of the copyright owner, The Endocrine Society. From the time of acceptance following peer review, the full text of this manuscript is made freely available by The Endocrine Society at http://www.endojournals.org/. The final copy edited article can be found at http://www.endojournals.org/. The Endocrine Society disclaims any responsibility or liability for errors or omissions in this version of the manuscript or in any version derived from it by the National Institutes of Health or other parties. The citation of this article must include the following information: author(s), article title, journal title, year of publication, and DOI.”

There are several important reasons we ask you to do this. Most important to you, as an author, is that we want the citations to your article to be accurately recorded and counted. Also we believe it is essential that the reader at the PMC site know that your accepted manuscript is not the final version of record (after the copy editing and your corrections) and that the reader be directed to the final version. Note that The Endocrine Society will provide PMC with your final edited version of the article and it will replace any accepted unedited manuscript version after the 12-month embargo period.

If you decide to send PMC your unedited accepted manuscript, we ask that authors follow the instructions above for the following reasons:

• The manuscript provided to the NIH by the author must be the identical manuscript, including the required attribution/disclaimer statement that has been accepted for publication by The Endocrine Society. Authors must ensure that this attribution/disclaimer statement required by The Endocrine Society is still in place when the proof of the reconfigured and XML tagged manuscript is sent by PMC for the author’s review.
• As the author-grantee principal investigator, you must submit your accepted manuscript at a secure Web site following the NIH file format requirements (a wide range of electronic word processing formats or PDF). For a full description of the submission procedures, please visit the PMC Web site at http://nihms.nih.gov. After you submit the manuscript to PMC, PMC will reconfigure your manuscript to comply with a standard PMC format, (i.e., on PMC it will likely look different from your accepted manuscript on The Endocrine Society Rapid Electronic Publications site.)
• When you submit accepted manuscripts to PMC, the NIH requests that you (only the principal investigator may do this) designate when your accepted, unedited, manuscript may be posted on PMC for public access. This designation will be in the form of a delay period from final publication by the publisher. The Endocrine Society permits, and requests, you to designate no delay from the date of print (final) publication by the Endocrine Society, i.e., a delay of 0 (zero), if posting your accepted unedited manuscript. Note that PMC will be able to determine the date of print (final) publication.
• The Endocrine Society will later replace the author’s unedited manuscript in PMC with The Endocrine Society’s final version of the article. You, as the author, may not submit the final, copy edited article to PMC.
• Copyright remains with The Endocrine Society, which invests time and effort to review the accepted manuscript, print and post online the final edited version of the manuscript, and archive your research findings.

Revised and posted: 4 March 2008